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★ ★ ★ ★ ★ 4.8 · 31,002+ Blissta customers

PainBloc® PEA 1200mg

Daily comfort starts with a compound your body already makes. 1200 mg of micronized PEA plus co-micronized luteolin to support everyday comfort.†

  • Everyday comfortMicronized PEA 1200 mg
  • Nerve healthPEA + Luteolin
  • Healthy inflammatory responseLuteolin 120 mg
  • AbsorptionMicronized form
  • Restful nightsComfort that lasts
  • Made by your bodyNaturally occurring
263 of 4,000 monthly bundles left 93%

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30-Day Money-Back Guarantee

Try it for 30 days from delivery. If it's not for you, we refund the product price. Keep the bottle. No questions asked.

Patty M.

“Life changing for my fibro. I’ve tried every supplement on Amazon and every prescription my doctor suggested. This is the first thing that’s actually worked. Sleep improved first, then the pain started dropping. Two months in and I feel like a different person.”

Patty M., USA · Verified Purchase ★★★★★

The Stack

Everything You Need to Know

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Product Overview
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Blissta® PainBloc, proprietary PEA + Luteolin formula. Micronized Palmitoylethanolamide at 1200mg, co-micronized with 120mg luteolin. PEA is a natural fatty acid compound your body already produces, your built-in defense against pain and inflammation. After 45, your body stops making enough. Luteolin works alongside it to push the effect deeper and make it last longer.

What makes ours different: most PEA products stop at PEA. Ours co-micronizes both compounds together for 3x absorption. Manufactured in a GMP-certified facility. Every batch third-party tested with a publicly available Certificate of Analysis.

  • Palmitoylethanolamide (PEA), 1200mg, micronized
  • Luteolin, 120mg, co-micronized
  • Vegetable cellulose capsule (vegan)
  • Zero fillers · zero magnesium stearate · zero GMOs
  • 60 capsules per bottle
⚙️
How It Works
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PEA activates PPAR-alpha receptors inside your cells, the master switches that control inflammation at the genetic level. Luteolin amplifies the effect by calming the same overactive cells from a second angle. Unlike CBD (works outside the cell) or gabapentin (blocks signals), this blend goes inside the cell to address the root cause.

1 · Calms mast cells. PEA and luteolin together tell overactive immune cells to stand down. Quiets the inflammation flood.

2 · Quiets glial cells. Restores normal nerve signal filtering. Stops pain amplification.

3 · Activates PPAR-alpha. Nuclear receptors that control inflammation at the gene level.

4 · Restores the system. Pain decreases, sleep improves, mood stabilizes, all at once.

Dosing: Loading phase (days 1 to 30): 2 capsules daily · Maintenance (day 31+): 1 capsule daily

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Key Benefits
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  • Chronic pain reduction. 11 RCTs across 774 patients showed statistically significant pain reduction (p = 0.00001).
  • Compounding relief. 2024 meta-analysis: 35% reduction in month 1, a further 35% in month 2. Gets better, not worse.
  • Sleep improvement. Most users notice better sleep within 2 to 3 weeks. Not sedation, recovery.
  • Nerve pain support. First-line neuropathic pain treatment in Italy. Diabetic neuropathy trial: significant reduction (P ≤ 0.001).
  • Fibromyalgia relief. Addresses mast cells and glial cells simultaneously. No pharmaceutical does this.
  • Zero side effects. 600+ clinical studies: zero major adverse events. No weight gain, no withdrawal, no tolerance.

† These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

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Ingredients & Purity
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Per serving (2 capsules):

Micronized Palmitoylethanolamide (PEA), 1200mg: Clinical trial dose. 3x absorption vs standard PEA.

Co-Micronized Luteolin, 120mg: Works alongside PEA to deepen and extend the effect. The reason ours outperforms plain PEA.

What’s not in it: no fillers, no magnesium stearate, no rice flour, no maltodextrin, no artificial colors, no GMOs, gluten or soy.

Tested for: 99%+ purity verified, heavy metal free, micronized particle size, GMP-certified facility.

Why co-micronized matters: standard PEA has poor absorption, most passes through. Co-micronizing PEA with luteolin reduces particle size so your body can use both, and the two compounds reinforce each other. Every clinical trial showing results used micronized PEA.

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Shipping & Guarantee
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Shipping. Ships within 24 hours Mon to Fri. Orders before 2 PM ET ship same day. Standard delivery 3 to 5 business days. Expedited options at checkout. Tracking emailed within 24 hours of dispatch.

30-Day Money-Back Guarantee. Try it for 30 days from delivery. If it’s not for you, email Riley at hello@blissta.co with your order number and we refund the product price within 24 hours. No questions asked. No return required. Keep the bottle.

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Real results

What Real Pain Sufferers Say About PainBloc

25,000+ customers. Real people. Real pain relief.

Jill Foster
★★★★★

"12 years of fibromyalgia. Tried gabapentin (zombie), Lyrica (40 pounds), CBD (placebo). My doctor was out of ideas. Found PEA through my own research. Sleep improved by week 2. By week 6, pain dropped noticeably. Three months in — cut my gabapentin in half with doctor guidance. This should have been offered to me a decade ago."

Jill Foster · Verified Purchase
Kimberley M. Huntington
★★★★★

"20+ years of chronic pain and $30,000 wasted on supplements. Expected nothing. Sleep came first — around day 10 I stopped waking at 2am. By week 5 I was reaching for ibuprofen less. By month 2, I got on the floor to play with my granddaughter and got back up without help. I cried — from relief that something finally worked."

Kimberley M. Huntington · Verified Purchase
Kindle Customer
★★★★★

"Works. Not overnight — took a solid 3-4 weeks. But once it kicked in, the difference was undeniable. I ran the 'pause test' — skipped it for 4 days and the pain came roaring back within 48 hours. Restarted immediately. Now I'm subscribed. Only complaint: wish I'd found this 5 years ago instead of wasting money on CBD and Amazon supplements that did nothing."

Kindle Customer · Verified Purchase
Eva Brown
★★★★★

"Nerve pain in both feet from diabetes. Nothing touched it — not gabapentin, not lidocaine patches, not the TENS unit. Shower water felt like fire. Started PainBloc at loading dose. By week 3, showers weren't torture anymore. By month 2, I can walk my dog around the block again. My wife noticed before I did — said I stopped wincing getting out of bed."

Eva Brown · Verified Purchase
The hidden piece

Why comfort gets harder after 45.

Your body makes its own comfort compound. It's called PEA. With age and everyday wear, your levels may not keep up with what your body needs.

Why comfort gets harder after 45
01
Age 20 to 40Your body kept up
Your cells make PEA on demand. A hard workout, a long day, a stressful week, and your body brought things back into balance. You bounced back fast. You slept through the night.
02
Age 45+Demand outpaces supply
With age and daily wear, your body may not keep up the way it used to. You don't notice at first. Then bouncing back takes longer. Stiff mornings start to feel normal.
03
Mast cellsThe alarm stays on
PEA helps keep your body's natural immune response in balance. When levels run low, it's harder to settle down after everyday stress. The stiffness getting out of bed. The restless nights. The "something's off" feeling.
04
Glial cellsThe volume stays up
Glial cells support and protect your nerves, and PEA helps keep them balanced. When it runs low, everyday sensations can feel louder than they should.
05
The cycleMore bottles, same mornings
Most people try one thing after another. Something stronger, another bottle, a new routine. Meanwhile nobody looked at what your body was making less of.

Not another quick fix. Support for what your body already makes.

Try PainBloc Risk-Free
30-day money-back guarantee. Keep the bottle either way.
The research

Decades of research. 600+ published studies.

PEA was first identified in the 1950s. Since then it has been studied by researchers around the world, including the lab of Nobel laureate Dr. Rita Levi-Montalcini.

PEA research
600+
Published studies
Peer-reviewed papers on PEA and how it works in the body.
1957
First identified
Nearly 70 years of scientific interest in this naturally occurring compound.
RCTs
Human trials
Studied in randomized controlled trials in adults.
20+ yrs
Used in Europe
Used as a nutritional ingredient in Europe for more than two decades.

*Research refers to PEA as an ingredient, not to PainBloc specifically. Full citations available on request.

How PEA works at cellular level
The mechanism

How does PEA actually work?

PEA works by restoring your body's natural pain defense system, the one that broke down with age. It activates PPAR-alpha receptors inside your cells, calming the overactive mast cells and glial cells generating inflammation and amplifying pain signals.

Unlike painkillers that mask symptoms for hours, PEA rebuilds the system that was supposed to manage pain on its own. That's why it works better over time, not worse. And that's why it helps with pain, sleep, mood, and anxiety simultaneously, because mast cells and glial cells influence all of those systems.

Beyond pain, PEA has been studied for its neuroprotective properties, supporting healthy nerve function.

Calm the cells. Everything downstream improves.
Clinical precision

Backed by science. Formulated with precision.

600+ scientific studies support the effectiveness of micronized Palmitoylethanolamide. Blissta PainBloc is formulated to restore your body's natural defense against pain and inflammation, nothing else added, nothing cut.

We use the exact form of PEA validated in clinical trials: micronized, at 1200mg, co-micronized with 120mg luteolin. Most PEA products stop at PEA. Ours doesn't. Every batch is manufactured in a GMP-certified facility under rigorous quality control.

✓Proprietary PEA + Luteolin
✓Co-Micronized (3x absorption)
✓1200mg Clinical Dose
✓GMP-Certified
PEA clinical research data
The protocol

Your daily comfort routine.

Take it every day. Give it time to build. Then check in with how you feel.

Blissta PainBloc morning routine
01
Days 1 to 30

Build it up

4 capsules daily (2 morning, 2 evening, with food), 1200 mg total. PEA works best with steady daily use, so the only goal this month is not to miss a day.

02
Weeks 2 to 4

Notice your nights

Many people say the first thing they notice is how they sleep. Keep a simple note each morning of how you slept and how you feel.

03
Day 31+

Settle into maintenance

Many people move to 2 capsules daily (600 mg). Around week 6 to 8, compare how you feel now to your notes from week one. That's your honest answer.

*Individual results vary. Always consult your healthcare provider before starting. Do not stop prescription medications without physician supervision.

The real difference

Not all PEA is the same. Here's what to look for.

The word on the front can match. What's inside, and how well your body can use it, often doesn't.

Typical PEA supplement
Blissta PainBloc
✕Often standard, non-micronized PEA
✓Micronized PEA for better absorption
✕PEA on its own
✓Co-micronized with 120 mg luteolin
✕Lower or unclear dose per serving
✓1200 mg daily, printed on the label
✕Testing info often not shared
✓Third-party tested
✕Unclear where it's made
✓Made in a GMP-certified facility
✕No guarantee
✓30-day money-back guarantee

PEA has been used in Europe for 20+ years. Most Americans have never heard of it.

PainBloc is a dietary supplement, not a replacement for prescribed medication. Never stop or change a prescription without your doctor.

Blissta PainBloc PEA
The difference

Why choose Blissta.

There are 200+ PEA products on Amazon. Most cut corners where it matters most: particle size, dose, sourcing. We built PainBloc on the opposite philosophy.

Micronized form. Clinical dose. GMP-certified manufacturing. Third-party tested with a public Certificate of Analysis, because if you can't verify what's in the bottle, you shouldn't be swallowing it.

✓99%+ Verified Purity
✓3rd Party Lab Tested
✓Zero Fillers · Zero Junk
✓25,000+ Customers
✓Public COA
✓30-Day Guarantee
30Days
The guarantee

If it doesn't work, email Riley. Refund in 24 hours.

Try it for 30 days from delivery. If it's not for you, email hello@blissta.co with your order number and we refund the product price within 24 hours. No questions. Keep the bottle.

✓ Product price refunded✓ No return shipping✓ No questions asked
Try PainBloc Risk-Free

Riley · Customer Care, Blissta

You asked

Frequently asked questions.

Straight answers. No hedge words. No fine print.

Blissta PainBloc PEA
What is PEA and how is it different from CBD?

PEA (Palmitoylethanolamide) is a natural fatty acid compound your body already produces. Unlike CBD, which has 16 failed clinical trials for chronic pain (University of Bath, 2024), PEA has 11 successful randomized controlled trials across 774 patients. CBD works on receptors outside your cells. PEA activates PPAR-alpha receptors inside your cells.

How is this different from gabapentin or Lyrica?

Gabapentin and Lyrica numb pain signals, which is why they can cause brain fog, weight gain, and withdrawal. PEA calms the mast cells and glial cells generating inflammation and amplifying pain. It has a strong safety profile across 600+ studies. PainBloc is a supplement, not a replacement for any prescription.

How long does it take to work?

Most users notice sleep improving within 2 to 3 weeks. Pain support typically builds over 4 to 8 weeks. Clinical studies showed a 35% reduction in month one and another 35% in month two. PEA builds over time.

What's the recommended dosing protocol?

Loading phase (first 30 days): 4 capsules daily, 2 morning and 2 evening, with food (1200mg total). Maintenance (day 31+): 2 capsules daily (600mg). This matches the clinical trial protocol that produced the strongest results.

Can I take this with my current medications?

PEA is generally well tolerated, but it can interact with some pain medications. If you take any prescription medication, check with your doctor or pharmacist before starting PainBloc.

Are there any side effects?

Across 600+ clinical studies, no major adverse events have been attributed to PEA. No weight gain. No brain fog. No withdrawal. No tolerance buildup. One of the cleanest safety profiles of any pain-support compound studied.

Can I taper off gabapentin with PEA?

PainBloc isn't a replacement for any prescription. Never stop or change gabapentin on your own. It needs slow, careful tapering under medical supervision, and stopping suddenly can cause serious withdrawal. Talk to your doctor about any change.

Why is the "micronized" form important?

PEA is a fatty compound with poor water solubility. Standard PEA particles are too large for efficient absorption, so most passes through. Micronization reduces particle size so your body can actually use it (1.75x higher plasma levels vs standard PEA). Every clinical trial showing significant results used micronized or ultramicronized PEA.

What's the "pause test" people keep mentioning?

After 6 to 8 weeks of consistent use, skip PEA for 3 days. If discomfort comes back within 48 to 72 hours, you have your answer from your own body, not from us. Most subscribe right after the pause test.

How long does one bottle last?

Loading phase (month 1): one bottle lasts ~30 days at 4 capsules/day. Maintenance (month 2+): one bottle lasts ~60 days at 2 capsules/day. The Buy 2 Get 1 Free bundle covers your full loading phase plus two months of maintenance.

Pregnant, nursing, or under 18?

Not recommended during pregnancy, nursing, or for anyone under 18. Consult your physician before use.

What's your refund process?

30-day money-back guarantee from the day your order is delivered. Email hello@blissta.co with your order number and we refund the product price within 24 hours. No return required, keep the bottle. No questions asked.

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